Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | UMPS | P11172 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formycin SCHEMBL980049 | 0.86 | HIF1A (0.61) | HIF1AUMPSPYGLSMN1; SMN2STAT6 | |
| Formycin SCHEMBL15262901 | 0.86 | HIF1A (0.61) | HIF1AUMPSPYGLSMN1; SMN2STAT6 | |
| Formycin SCHEMBL14074914 | 0.86 | HIF1A (0.61) | HIF1AUMPSPYGLSMN1; SMN2STAT6 | |
| SCHEMBL5071995 | 0.79 | HIF1A (0.44) | HIF1APYGLKDM4EGMNNLMNA | |
| Formycin B SCHEMBL29420243 | 0.77 | PNP (0.52) | HIF1AUMPSPYGL | |
| SCHEMBL22399466 | 0.77 | HIF1A (0.50) | HIF1AUMPSSMN1; SMN2STAT6SLC29A1 | |
| Formycin SCHEMBL28203182 | 0.76 | HIF1A (0.50) | HIF1AUMPSPYGLSMN1; SMN2STAT6 | |
| Deaminoformycin SCHEMBL5071997 | 0.76 | HIF1A (0.46) | HIF1AUMPSPYGLKDM4EGMNN | |
| Deaminoformycin SCHEMBL14217783 | 0.76 | HIF1A (0.46) | HIF1AUMPSPYGLKDM4EGMNN | |
| SCHEMBL1796867 | 0.73 | HIF1A (0.54) | HIF1APYGLKDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368437-B1 | Bicyclic heterocycles, processes for their preparation and their use as herbicides and pharmaceutical agents | BAYER CROPSCIENCE AG (DE) | 2008-05-06 | — | — | US | disclosed |