Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.45 |
| ▸ | PPARG | P37231 | 11/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072161 | 1.00 | PPARA (0.45) | PPARAPPARGFFAR1VDRPPARD | |
| SCHEMBL5017295 | 0.92 | PPARA (0.46) | PPARAPPARGFFAR1VDRPPARD | |
| SCHEMBL5017299 | 0.92 | PPARA (0.46) | PPARAPPARGFFAR1VDRPPARD | |
| SCHEMBL5024486 | 0.86 | PPARA (0.44) | PPARAPPARGFFAR1VDRPPARD | |
| SCHEMBL5018056 | 0.83 | PPARG (0.52) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5018058 | 0.83 | PPARG (0.52) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5024784 | 0.78 | PPARA (0.48) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5024780 | 0.78 | PPARA (0.48) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5024601 | 0.75 | PPARA (0.44) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5016013 | 0.75 | PPARA (0.44) | PPARAPPARGFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551814-B1 | CHIRALE OXAZOLE-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | claimed |