Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.75 |
| ▸ | PPARG | P37231 | 12/20 | 0.75 |
| ▸ | PPARD | Q03181 | 6/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077573 | 0.93 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL4557472 | 0.86 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5077559 | 0.84 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL5072630 | 0.83 | PPARD (0.75) | PPARAPPARGPPARD | |
| SCHEMBL5072643 | 0.81 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL5078430 | 0.81 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL6797366 | 0.81 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5074498 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5074799 | 0.81 | PPARA (0.77) | PPARAPPARGPPARD | |
| SCHEMBL5074542 | 0.80 | PPARA (0.65) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539136-B1 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO INC (US) | 2008-07-09 | — | — | EP | claimed |