SCHEMBL5073187

SCHEMBL5073187

CCCCCC1(C(=O)O)CCCC1OC(=O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
CHRNA7 P36544 2/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA5 P30532 1/20 0.38
CHRNA4 P43681 1/20 0.38
LMNA P02545 1/20 0.38
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
KCNH2 Q12809 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5072413 0.99 BCHE (0.39) BCHEMEN1KMT2AGAACHRNA7
SCHEMBL6060735 0.99 BCHE (0.39) BCHEMEN1KMT2AGAACHRNA7
SCHEMBL5069938 0.96 BCHE (0.40) BCHEMEN1KMT2AGAACHRNA7
SCHEMBL6060825 0.91 KMT2A (0.40) BCHEMEN1KMT2AGAACHRNA7
SCHEMBL4812333 0.91 BCHE (0.40) BCHEMEN1KMT2AGAACHRNA7
SCHEMBL4815273 0.90 AKT1 (0.41) BCHEMEN1KMT2AKCNH2ALDH1A1
SCHEMBL4809896 0.89 AKT1 (0.48) LMNAAKT1
SCHEMBL4805188 0.88 AKT1 (0.50) LMNAAKT1
SCHEMBL6060683 0.87 CHRNA7 (0.38) MEN1KMT2AGAACHRNA7CHRNB2
SCHEMBL4814743 0.87 BCHE (0.41) BCHEMEN1KMT2AGAACHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008517957-A 2008-05-29 JP claimed
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO claimed
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed