Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718925 | 0.87 | GAA (0.44) | GAAMEN1MAPTKMT2A | |
| SCHEMBL11462556 | 0.81 | GAA (0.46) | GAAHTTMEN1MAPTKMT2A | |
| SCHEMBL8949027 | 0.80 | GAA (0.41) | GAANAAAEPHX1TSHREPHX2 | |
| SCHEMBL7570685 | 0.80 | GAA (0.41) | GAANAAAEPHX1TSHREPHX2 | |
| SCHEMBL725877 | 0.79 | GAA (0.33) | GAANAAAEPHX1TSHREPHX2 | |
| SCHEMBL725876 | 0.79 | GAA (0.33) | GAANAAAEPHX1TSHREPHX2 | |
| SCHEMBL11500771 | 0.78 | GAA (0.41) | GAANAAAMEN1MAPTKMT2A | |
| SCHEMBL8948954 | 0.77 | HTR2C (0.48) | NAAAEPHX2RAD52NPSR1FAAH | |
| SCHEMBL20438833 | 0.77 | ESR1 (0.44) | GAAMAPTALDH1A1 | |
| SCHEMBL20429045 | 0.77 | GAA (0.36) | GAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263855-B1 | STABILIZER MIXTURES FOR POLYOLEFINS | CIBA SC HOLDING AG (CH) | 2008-03-12 | — | — | EP | claimed |
| EP-1077227-B1 | Stabilizer mixtures | CIBA SC HOLDING AG (CH) | 2006-06-07 | — | — | EP | claimed |