SCHEMBL5073457

SCHEMBL5073457

CC1NC(=O)C(C)OC1=O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
PARP1 P09874 1/20 0.35
CYP2C19 P33261 1/20 0.33
BRPF1 P55201 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13311337 0.95 TSHR (0.34) TSHRPARP1CYP2C19
SCHEMBL15195476 0.75 CA1 (0.32)
SCHEMBL14612064 0.74
SCHEMBL6375014 0.73 PARP1 (0.32) PARP1
SCHEMBL21023424 0.72 PARP1 (0.31) PARP1
SCHEMBL13399686 0.68 TSHR (0.58) TSHRBRPF1CREBBP
SCHEMBL16316014 0.68 TSHR (0.58) TSHRBRPF1CREBBP
SCHEMBL12809719 0.68 TSHR (0.58) TSHRBRPF1CREBBP
SCHEMBL1226598 0.68 TSHR (0.58) TSHRBRPF1CREBBP
SCHEMBL13074412 0.68 TSHR (0.58) TSHRBRPF1CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620189-B Preparation method of layered three-dimensional nano-sheet 河北工业大学 2024-11-08 CN claimed
CN-118620189-A Preparation method of layered three-dimensional nano-sheet 河北工业大学 2024-09-10 CN claimed
US-11015021-B2 Method for preparation of a polyester NANJING TECH UNIVERSITY (CN) 2021-05-25 US claimed
US-20200140608-A1 METHOD FOR PREPARATION OF A POLYESTER NANJING TECH UNIVERSITY (CN) 2020-05-07 US claimed
EP-2647656-A2 Bioresorbable and biocompatible thermoplastic elastomer having a shape memory, particularly for biomedical applications and a process for their preparation Centrum Materialów Polimerowych i Weglowych PAN (PL) 2013-10-09 EP claimed
CN-113677423-B Graft copolymer film and nanoporous polypropylene film having polypropylene backbone SABIC环球技术有限责任公司 2025-02-25 CN disclosed
US-12215199-B2 Polypropylene backbone, and nanoporous polypropylene membrane SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-02-04 US disclosed
CN-118620189-B Preparation method of layered three-dimensional nano-sheet 河北工业大学 2024-11-08 CN disclosed
CN-118620189-A Preparation method of layered three-dimensional nano-sheet 河北工业大学 2024-09-10 CN disclosed
US-20220169802-A1 FILM FROM GRAFT COPOLYMER HAVING A POLYPROPYLENE BACKBONE, AND NANOPOROUS POLYPROPYLENE MEMBRANE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-06-02 US disclosed
EP-3946698-A1 FILM FROM GRAFT COPOLYMER HAVING A POLYPROPYLENE BACKBONE, AND NANOPOROUS POLYPROPYLENE MEMBRANE SABIC Global Technologies, B.V. (NL) 2022-02-09 EP disclosed
CN-113677423-A Graft copolymer film having polypropylene skeleton and nanoporous polypropylene film SABIC环球技术有限责任公司 2021-11-19 CN disclosed
US-20050163822-A1 Biodegradable bio-absorbable material for clinical practice and method for producing the same GOODMAN CO., LTD. (JP) 2005-07-28 US disclosed
EP-0619732-B1 BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION MASSACHUSETTS INST TECHNOLOGY (US) 2001-01-31 EP disclosed
US-5466801-A Process for the preparation of 3-, 6-substituted 2,5-morpholinediones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-11-14 US disclosed
US-5399665-A Reacting an alpha-amino acid with an alpha-hydroxy acid to form a morpholinedione, polymerizing morpholinedione with Lewis acid; biologically active moieties may be coupled to the polymer MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1995-03-21 US disclosed
EP-0619732-A4 BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION. MASSACHUSETTS INST TECHNOLOGY (US) 1995-02-22 EP disclosed
EP-0619732-A1 BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1994-10-19 EP disclosed
WO-1994009760-A1 BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1994-05-11 WO disclosed
WO-1994003441-A1 PROCESS FOR THE PREPARATION OF 3-, 6-SUBSTITUTED 2,5-MORPHOLINEDIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-17 WO disclosed