SCHEMBL5073871

SCHEMBL5073871

[CH2]CCCCCCCCCCCCCCCCCCSCC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
CES2 O00748 1/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
BLM P54132 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3294853 1.00
SCHEMBL9474435 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL6968146 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL5143773 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL10887421 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL6625515 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL6236722 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL9474203 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL7839905 1.00 TSHR (0.41) TSHRCES2GMNNTP53POLB
SCHEMBL3286864 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697465-B1 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GEN ELECTRIC (US) 2008-02-13 EP disclosed
EP-1697465-A2 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2006-09-06 EP disclosed
WO-2005061623-A2 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2005-07-07 WO disclosed
US-20050137310-A1 Polymer nanocomposites and methods for their preparation CITIBANK, N.A., AS COLLATERAL AGENT 2005-06-23 US disclosed