Ethylene

Ethylene

SCHEMBL5074085

C=C.CCOC(C)OCC.CCOc1ccc(C2CCCCC2)c(F)c1F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 7/20 0.36
FEN1 P39748 4/20 0.35
ALOX5AP P20292 3/20 0.35
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGDR Q13258 3/20 0.34
APOBEC3G Q9HC16 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.34
CAMKK1 Q8N5S9 1/20 0.33
CAMKK2 Q96RR4 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15681397 0.88 PTGDR2 (0.43) PTGDR2LMNAHTTPTGDRAPOBEC3G
Ethylene SCHEMBL5076561 0.86 HCRTR2 (0.33) PTGDR2ALDH1A1MAPT
SCHEMBL19986372 0.82 PTGDR2 (0.40) PTGDR2FEN1ALOX5APLMNAHTT
SCHEMBL14922531 0.80 KDM1A (0.41) PTGDR2LMNAHTTAPOBEC3GALDH1A1
SCHEMBL15684602 0.80 PTGDR2 (0.40) PTGDR2FEN1ALOX5APPTGDRALDH1A1
SCHEMBL18949939 0.80 PTGDR2 (0.37) PTGDR2LMNAHTTPTGDRAPOBEC3G
SCHEMBL15684611 0.78 HTR1D (0.44) PTGDR2FEN1ALOX5APPTGDR
SCHEMBL26209548 0.78 CAMKK1 (0.36) PTGDR2FEN1ALOX5APLMNAHTT
SCHEMBL25929345 0.78 CAMKK1 (0.36) PTGDR2FEN1ALOX5APLMNAHTT
SCHEMBL16768995 0.78 CAMKK1 (0.36) PTGDR2FEN1ALOX5APLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362839-B1 Liquid crystal composition having a positive delta-epsilon and liquid crystal display device CHISSO CORP (JP) 2008-08-13 EP disclosed
US-7081279-B2 Alkenyl compound having a negative Δε value, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2006-07-25 US disclosed
US-20040065866-A1 Alkenyl compound having a negative delta epsilon value, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2004-04-08 US disclosed
EP-1362839-A2 Liquid crystal composition having a delta-epsilon- of not less than zero and liquid crystal display device CHISSO CORPORATION (JP) 2003-11-19 EP disclosed
EP-0969071-B1 Alkenyl compound having a negative delta epsilon value, liquid crystal composition and liquid crystal display device CHISSO CORP (JP) 2003-11-05 EP disclosed
EP-0969071-A1 Alkenyl compound having a negative delta epsilon value, liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2000-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040065866-A1 Alkenyl compound having a negative delta epsilon value, liquid crystal composition, and liquid crystal display device CTNND1, CCT4, DLK1 PTGDR2 723/4885FEN1 958/4885ALOX5AP 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.