SCHEMBL5074499

SCHEMBL5074499

CO/C=C(/C(=O)OC)c1ccccc1COc1cc(Cl)c(OC(F)(F)C(F)OC(F)(F)F)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.38
SCN9A Q15858 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150429 0.92 HIF1A (0.33) HIF1ASCN9AMRGPRX4
SCHEMBL6150433 0.92 HIF1A (0.33) HIF1ASCN9AMRGPRX4
SCHEMBL5074553 0.92 HIF1A (0.39) HIF1ASCN9AMRGPRX4MEN1KMT2A
SCHEMBL5074510 0.90 HIF1A (0.38) HIF1ASCN9AMRGPRX4MEN1KMT2A
SCHEMBL5076935 0.85 HIF1A (0.55) HIF1ASCN9AMRGPRX4MEN1KMT2A
SCHEMBL6149508 0.84 TP53 (0.36) HIF1AMRGPRX4
SCHEMBL6149505 0.84 TP53 (0.36) HIF1AMRGPRX4
SCHEMBL5074501 0.82 HIF1A (0.35) HIF1ASCN9AMRGPRX4MEN1KMT2A
SCHEMBL5079611 0.81 MRGPRX4 (0.39) HIF1ASCN9AMRGPRX4
SCHEMBL5079624 0.81 MRGPRX4 (0.39) HIF1ASCN9AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885SCN9A 1765/4885MRGPRX4 989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.