Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167103 | 0.92 | — | — | |
| SCHEMBL210276 | 0.92 | — | — | |
| SCHEMBL5998620 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL8539702 | 0.90 | — | — | |
| SCHEMBL8614325 | 0.85 | APEX1 (0.33) | APEX1PTGS1AKR1C3ALDH1A1 | |
| Propane SCHEMBL17224456 | 0.85 | APEX1 (0.33) | APEX1PTGS1AKR1C3ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28476954 | 0.76 | TSHR (0.40) | ALDH1A1 | |
| SCHEMBL1865884 | 0.73 | PTGS1 (0.37) | APEX1PTGS1AKR1C3ALDH1A1 | |
| SCHEMBL1865885 | 0.73 | PTGS1 (0.37) | APEX1PTGS1AKR1C3ALDH1A1 | |
| SCHEMBL17755551 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197227-B9 | METHOD OF THE ADMINISTRATION OF DRUGS HAVING BINDING AFFINITY WITH PLASMA PROTEIN AND PREPARATION TO BE USED IN THE METHOD | NIHON MEDIPHYSICS CO LTD (JP) | 2008-06-11 | — | — | EP | claimed |
| EP-1197227-B1 | METHOD OF THE ADMINISTRATION OF DRUGS HAVING BINDING AFFINITY WITH PLASMA PROTEIN AND PREPARATION TO BE USED IN THE METHOD | NIHON MEDIPHYSICS CO LTD (JP) | 2007-09-12 | — | — | EP | claimed |