Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079568 | 1.00 | PTPN11 (0.40) | PTPN11TP53HTTMRGPRX4THRB | |
| SCHEMBL5079562 | 1.00 | PTPN11 (0.40) | PTPN11TP53HTTMRGPRX4THRB | |
| SCHEMBL5074567 | 1.00 | PTPN11 (0.40) | PTPN11TP53HTTMRGPRX4THRB | |
| SCHEMBL5080510 | 0.93 | TP53 (0.39) | TP53HTTMRGPRX4BCL2MCL1 | |
| SCHEMBL5080504 | 0.93 | TP53 (0.39) | TP53HTTMRGPRX4BCL2MCL1 | |
| SCHEMBL6150419 | 0.91 | PTPN11 (0.41) | PTPN11THRBTHRAPLK1TSHR | |
| SCHEMBL6150427 | 0.91 | PTPN11 (0.41) | PTPN11THRBTHRAPLK1TSHR | |
| SCHEMBL5074570 | 0.91 | PTPN11 (0.42) | PTPN11TP53HTTMRGPRX4THRB | |
| SCHEMBL5079564 | 0.91 | PTPN11 (0.42) | PTPN11TP53HTTMRGPRX4THRB | |
| SCHEMBL5080378 | 0.89 | TP53 (0.39) | TP53HTTMRGPRX4BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435844-B2 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2008-10-14 | — | — | US | disclosed |
| US-20060235075-A1 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2006-10-19 | — | — | US | disclosed |
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235075-A1 | Analogous compounds of strobilurines and their use as acaricides and insecticides | DDT, RYR1, TPMT | PTPN11 461/4885TP53 2842/4885HTT 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.