SCHEMBL5075112

SCHEMBL5075112

CC1(CCCCC(=O)O)CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.37
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
EPHX2 P34913 3/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALOX5 P09917 1/20 0.33
TSHR P16473 4/20 0.32
AKR1B1 P15121 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
PPARG P37231 5/20 0.32
PPARD Q03181 5/20 0.32
PPARA Q07869 5/20 0.32
FFAR1 O14842 3/20 0.32
ESR1 P03372 2/20 0.32
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
SRD5A2 P31213 1/20 0.32
CASP6 P55212 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079078 0.89 CYP2D6 (0.37) PTGS1CYP2D6CYP2C19KDM4E
SCHEMBL1698056 0.83 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL1698126 0.77 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL1698125 0.77 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL5837346 0.76 EPHX2 (0.33) CYP2D6CYP2C19EPHX2ALOX5TSHR
SCHEMBL5837166 0.74 CYP2D6 (0.33) CYP2D6CYP2C19EPHX2LMNAALOX5
SCHEMBL3021891 0.72 CYP2D6 (0.36) CYP2D6CYP2C19KDM4E
SCHEMBL5837042 0.71 TSHR (0.33) CYP2D6CYP2C19EPHX2ALOX5TSHR
SCHEMBL12191675 0.71 CYP2D6 (0.40) CYP2D6CYP2C19
SCHEMBL250980 0.69 CYP2D6 (0.49) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1293521-B1 Cyclic olefin addition copolymer and process for producing same, crosslinkable composition, crosslinked product and process for producing same, and optically transparent material and application thereof JSR CORP (JP) 2008-02-13 EP disclosed
US-6992154-B2 Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof JSR CORPORATION (JP) 2006-01-31 US disclosed
US-20050107552-A1 Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof JSR CORPORATION (JP) 2005-05-19 US disclosed
US-6844403-B2 CYCLIC OLEFIN ADDITION COPOLYMER AND PROCESS FOR PRODUCING SAME, CROSSLINKING COMPOSITION, CROSSLINKED PRODUCT AND PROCESS FOR PRODUCING SAME, AND OPTICALLY TRANSPARENT MATERIAL AND APPLICATION THEREOF JSR CORPORATION (JP) 2005-01-18 US disclosed
US-20030119961-A1 Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof JSR CORPORATION (JP) 2003-06-26 US disclosed
EP-1293521-A2 Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof JSR Corporation (JP) 2003-03-19 EP disclosed