SCHEMBL5075138

SCHEMBL5075138

CCCOCC(CO[SiH2]C(C)(C)Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
MMP8 P22894 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075144 0.93 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5077364 0.89 SLC6A2 (0.36) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5081737 0.88 SLC6A2 (0.42) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5081560 0.87 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5078147 0.86 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5075139 0.82 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5081809 0.82 SLC6A2 (0.40) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5080808 0.82 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5078144 0.77 SLC6A2 (0.36) SLC6A2TAAR1LMNACYP2D6MMP8
SCHEMBL5085403 0.77 SLC6A2 (0.44) SLC6A2TAAR1LMNACYP2D6MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed