⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291467 | 0.73 | — | — | |
| SCHEMBL15314385 | 0.73 | — | — | |
| SCHEMBL7965356 | 0.71 | — | — | |
| SCHEMBL9402060 | 0.71 | — | — | |
| SCHEMBL20594214 | 0.71 | — | — | |
| SCHEMBL9486409 | 0.71 | — | — | |
| SCHEMBL15189297 | 0.69 | — | — | |
| SCHEMBL7775816 | 0.69 | — | — | |
| SCHEMBL1935360 | 0.69 | — | — | |
| SCHEMBL126062 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877064-A2 | DELIVERY OF TIGECYCLINE IN THE PRESENCE OF HEPARIN | Wyeth (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1877092-A2 | DELIVERY OF TIGECYCLINE IN THE PRESENCE OF WARFARIN | Wyeth (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006121666-A2 | DELIVERY OF TIGECYCLINE IN THE PRESENCE OF WARFARIN | WYETH (US) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006121713-A2 | DELIVERY OF TIGECYCLINE IN THE PRESENCE OF HEPARIN | WYETH (US) | 2006-11-16 | — | — | WO | disclosed |