SCHEMBL5075378

SCHEMBL5075378

C1=C(C2=C3\CCCCC3CCCCC/2)\CCCCCC/1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20574040 1.00 HDAC1 (0.33) HDAC1HDAC2
SCHEMBL2513476 0.95 HDAC1 (0.32) HDAC1HDAC2
SCHEMBL6905057 0.73 KMT2A (0.38) HDAC1HDAC2
SCHEMBL5775953 0.73 KMT2A (0.38) HDAC1HDAC2
SCHEMBL38654652 0.71 HDAC1 (0.36) HDAC1HDAC2
SCHEMBL5957937 0.71 HDAC1 (0.34) HDAC1HDAC2
SCHEMBL15819942 0.71 HDAC1 (0.34) HDAC1HDAC2
SCHEMBL4622927 0.71 HDAC1 (0.36) HDAC1HDAC2
SCHEMBL4622930 0.71 HDAC1 (0.36) HDAC1HDAC2
SCHEMBL18244171 0.70 TYMP (0.41) HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402707-B2 Method of preparation of a precursor oligocene KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-07-22 US claimed
US-20060166409-A1 Method of preparation of a precursor oligocene KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-07-27 US claimed
EP-1606239-A1 METHOD OF PREPARATION OF A PRECURSOR OLIGOCENE Koninklijke Philips Electronics N.V. (NL) 2005-12-21 EP claimed
WO-2004083160-A1 METHOD OF PREPARATION OF A PRECURSOR OLIGOCENE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-09-30 WO claimed
US-7402707-B2 Method of preparation of a precursor oligocene KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-07-22 US disclosed
US-20060166409-A1 Method of preparation of a precursor oligocene KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-07-27 US disclosed
EP-1606239-A1 METHOD OF PREPARATION OF A PRECURSOR OLIGOCENE Koninklijke Philips Electronics N.V. (NL) 2005-12-21 EP disclosed
WO-2004083160-A1 METHOD OF PREPARATION OF A PRECURSOR OLIGOCENE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-09-30 WO disclosed