⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875035 | 1.00 | — | — | |
| SCHEMBL28293206 | 0.71 | EPHX1 (0.35) | — | |
| SCHEMBL5391012 | 0.71 | — | — | |
| SCHEMBL9577980 | 0.69 | — | — | |
| SCHEMBL5393265 | 0.69 | — | — | |
| SCHEMBL23282968 | 0.69 | — | — | |
| SCHEMBL5076005 | 0.69 | — | — | |
| SCHEMBL5080361 | 0.69 | — | — | |
| SCHEMBL10866763 | 0.69 | — | — | |
| SCHEMBL11448607 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |
| US-9468661-B2 | Pyrrolidine derivatives and their use as complement pathway modulators | NOVARTIS AG (CH) | 2016-10-18 | — | — | US | disclosed |
| CN-104619698-B | Pyrrolidin derivatives and the purposes as complement pathway regulator thereof | 诺华股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| US-20150190457-A1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2015-07-09 | — | — | US | disclosed |
| EP-2867225-A1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | Novartis AG (CH) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014002054-A1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2014-01-03 | — | — | WO | disclosed |
| US-7435844-B2 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2008-10-14 | — | — | US | disclosed |
| US-20060235075-A1 | Analogous compounds of strobilurines and their use as acaricides and insecticides | ISAGRO RICERCA S.R.L. (IT) | 2006-10-19 | — | — | US | disclosed |
| EP-0137169-A2 | Cumalincarboxylic-acid esters, process for their preparation and agricultural fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0129889-A2 | An oxime derivative and its use as an insecticide or acaricide | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-01-02 | — | — | EP | disclosed |
| EP-0024649-B1 | 2,2-DICHLOROCYCLOPROPYL-METHYL-PHOSPHORIC ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1982-08-11 | — | — | EP | disclosed |
| US-4296108-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |
| EP-0024649-A1 | 2,2-Dichlorocyclopropyl-methyl-phosphoric acid derivatives, process for preparing them and their use in combating pests | BASF Aktiengesellschaft (DE) | 1981-03-11 | — | — | EP | disclosed |