Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29623584 | 0.78 | EGFR (0.73) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL185140 | 0.78 | EGFR (0.73) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1384741 | 0.78 | EGFR (0.73) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL7690931 | 0.76 | EGFR (0.60) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1386500 | 0.75 | EGFR (0.63) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1384221 | 0.75 | EGFR (0.63) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL14837536 | 0.74 | EGFR (0.59) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1386645 | 0.74 | EGFR (0.59) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1386399 | 0.74 | EGFR (0.59) | EGFRCITGAKEPHB6ABCC4 | |
| SCHEMBL1383540 | 0.74 | EGFR (0.59) | EGFRCITGAKEPHB6ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915155-A1 | DIHYDROPTERIDINONES IN THE TREATMENT OF RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2008-04-30 | — | — | EP | disclosed |
| EP-1799191-A1 | MODIFYING SURFACES OF LACTOSE SERVING AS AN AUXILIARY AGENT TO BE USED FOR POWDER INHALANTS | Boehringer Ingelheim International GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007014838-A1 | DIHYDROPTERIDINONES IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-08 | — | — | WO | disclosed |
| WO-2006037738-A1 | MODIFYING SURFACES OF LACTOSE SERVING AS AN AUXILIARY AGENT TO BE USED FOR POWDER INHALANTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-13 | — | — | WO | disclosed |