Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109797 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL6435429 | 0.82 | TSHR (0.39) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3398532 | 0.73 | TSHR (0.39) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL198829 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL199322 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL198695 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL200934 | 0.72 | — | — | |
| SCHEMBL200480 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL387241 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL198939 | 0.72 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1697465-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061623-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |