Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | EEF2K | O00418 | 2/20 | 0.54 |
| ▸ | EEF2 | P13639 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15329259 | 1.00 | CA1 (0.54) | CA1CA2KMT2AMEN1EEF2K | |
| Bromide SCHEMBL1330856 | 1.00 | CA1 (0.54) | CA1CA2KMT2AMEN1EEF2K | |
| Bromide SCHEMBL1330667 | 1.00 | CA1 (0.54) | CA1CA2KMT2AMEN1EEF2K | |
| Bromide SCHEMBL15329023 | 1.00 | CA1 (0.54) | CA1CA2KMT2AMEN1EEF2K | |
| Bromide SCHEMBL707781 | 1.00 | CA1 (0.54) | CA1CA2KMT2AMEN1EEF2K | |
| SCHEMBL5287245 | 0.98 | KMT2A (0.55) | CA1CA2KMT2AMEN1EEF2K | |
| SCHEMBL1501428 | 0.98 | KMT2A (0.55) | CA1CA2KMT2AMEN1EEF2K | |
| SCHEMBL1826845 | 0.98 | KMT2A (0.55) | CA1CA2KMT2AMEN1EEF2K | |
| SCHEMBL372335 | 0.98 | KMT2A (0.55) | CA1CA2KMT2AMEN1EEF2K | |
| SCHEMBL4068863 | 0.98 | KMT2A (0.55) | CA1CA2KMT2AMEN1EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288820-B | Organically modified attapulgite-dye hybrid pigment and preparation method and application thereof | 台州学院 | 2022-07-01 | — | — | CN | claimed |
| CN-113288820-A | Organically modified attapulgite-dye hybrid pigment and preparation method and application thereof | 台州学院 | 2021-08-24 | — | — | CN | claimed |
| CN-113288820-B | Organically modified attapulgite-dye hybrid pigment and preparation method and application thereof | 台州学院 | 2022-07-01 | — | — | CN | disclosed |
| CN-113288820-A | Organically modified attapulgite-dye hybrid pigment and preparation method and application thereof | 台州学院 | 2021-08-24 | — | — | CN | disclosed |
| CN-112086706-A | Heat dissipation method for power battery | 中国石油化工股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-112086704-A | Power battery heat dissipation device based on ionic liquid phase-change material | 中国石油化工股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-112086705-A | Power battery heat dissipation method based on ionic liquid phase change material and liquid cooling | 中国石油化工股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-112086707-A | Power battery heat dissipation device | 中国石油化工股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| US-20160194479-A1 | NANOCOMPOSITES CONTAINING LAYERED NANOPARTICLES AND DISPERSANT, COMPOSITES, ARTICLES, AND METHODS OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2016-07-07 | — | — | US | disclosed |
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1697465-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061623-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |