SCHEMBL5079439

SCHEMBL5079439

CNC(=O)/C(=N/OC)c1ccccc1COc1cc(Cl)c(OC/C=C(\F)C(F)(F)F)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.45
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PDK2 Q15119 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
SCN9A Q15858 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079443 1.00 HIF1A (0.45) HIF1AMEN1KMT2APDK2MRGPRX4
SCHEMBL5079434 1.00 HIF1A (0.45) HIF1AMEN1KMT2APDK2MRGPRX4
SCHEMBL5075848 0.92 HIF1A (0.47) HIF1AMEN1KMT2AMRGPRX4POLB
SCHEMBL5075851 0.92 HIF1A (0.47) HIF1AMEN1KMT2AMRGPRX4POLB
SCHEMBL5075843 0.92 HIF1A (0.47) HIF1AMEN1KMT2AMRGPRX4POLB
SCHEMBL5080502 0.91 HIF1A (0.55) HIF1AMEN1KMT2APDK2MRGPRX4
SCHEMBL5075807 0.91 HIF1A (0.47) HIF1AMEN1KMT2AMRGPRX4POLB
SCHEMBL5075804 0.91 HIF1A (0.47) HIF1AMEN1KMT2AMRGPRX4POLB
SCHEMBL5076967 0.91 HIF1A (0.44) HIF1AMEN1KMT2APDK2MRGPRX4
SCHEMBL5076964 0.91 HIF1A (0.44) HIF1AMEN1KMT2APDK2MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885MEN1 2918/4885KMT2A 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.