SCHEMBL5079499

SCHEMBL5079499

FC(F)(F)c1ccc(OCCCS)nc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.44
THRB P10828 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GABRA5 P31644 1/20 0.41
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.40
RXRA P19793 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2B Q13224 2/20 0.38
RAB9A P51151 1/20 0.38
LIPE Q05469 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077087 0.91 HPGD (0.48) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL3159889 0.84 HPGD (0.48) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL5079495 0.84 HPGD (0.48) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL5076062 0.83 MRGPRX4 (0.47) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL4699112 0.83 HPGD (0.47) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL10274190 0.83 HPGD (0.54) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL2127531 0.83 MRGPRX4 (0.47) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL2127040 0.83 HPGD (0.47) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL5077085 0.82 HPGD (0.49) HPGDKMT2AMAPK1TSHRSMN1; SMN2
SCHEMBL13347728 0.81 HPGD (0.52) HPGDKMT2AMAPK1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HPGD 3764/4885KMT2A 3499/4885MAPK1 3052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.