SCHEMBL507970

SCHEMBL507970

O=c1[nH]c2cc(Cl)ccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 1.00
KDM4E B2RXH2 3/20 0.61
ALDH1A1 P00352 3/20 0.61
GAA P10253 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2C9 P11712 1/20 0.61
HPGD P15428 1/20 0.61
PSMB8 P28062 1/20 0.61
CYP2C19 P33261 1/20 0.61
PGR P06401 1/20 0.56
PDE3B Q13370 3/20 0.53
PDE3A Q14432 3/20 0.53
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
GRIN2C Q14957 1/20 0.48
GRIN3A Q8TCU5 1/20 0.48
NPSR1 Q6W5P4 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30537992 1.00 CMA1 (1.00) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL6190902 0.86 CMA1 (0.75) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL3859325 0.77 CMA1 (0.59) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL30534236 0.76 CMA1 (0.61) CMA1KDM4EALDH1A1GAAPGR
SCHEMBL9497675 0.76 PSMB8 (1.00) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL8286761 0.76 CMA1 (0.61) CMA1ALDH1A1PGRPDE3BPDE3A
SCHEMBL289800 0.76 CMA1 (0.61) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL29477415 0.76 CMA1 (0.61) CMA1KDM4EALDH1A1GAACYP1A2
SCHEMBL30613119 0.76 CMA1 (0.61) CMA1KDM4EALDH1A1GAAHPGD
SCHEMBL3224706 0.76 CMA1 (0.61) CMA1KDM4EALDH1A1GAAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192458-A Thiazolinone-based acrylic acid silane ester self-polishing antifouling resin, and preparation method and application thereof 哈尔滨工程大学 2024-12-27 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
JP-57116057-A None JP disclosed
JP-57179175-A None JP disclosed
JP-56020582-A None JP disclosed
JP-56020581-A None JP disclosed
JP-59046278-A None JP disclosed
JP-58225075-A None JP disclosed
JP-61191677-A None JP disclosed
JP-56127365-A None JP disclosed
JP-S5946278-A NOVEL PROCESS FOR PREPARATION OF 5-CHLORO-2- BENZOTHIAZOLINONE DERIVATIVE TOUBISHI YAKUHIN KOGYO KK 1984-03-15 JP disclosed
JP-S58225075-A PREPARATION OF 5-CHLORO-2-BENZOTHIAZOLINONE DERIVATIVE SANYO KAGAKU KENKYUSHO:KK 1983-12-27 JP disclosed
EP-0022317-B1 2-OXO-BENZOTHIAZOLINE, BENZOXAZOLINE OR INDOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-21 EP disclosed
US-4370340-A ANTIDIABETIC AGENT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-01-25 US disclosed
JP-S57179175-A PREPARATION OF 2-BENZOTHIAZOLINONE DERIVATIVE OR SALT THEREOF KANO SHINZO 1982-11-04 JP disclosed
JP-S57116057-A PREPARATION OF 2-BENZOTHIAZOLINONE DERIVATIVE OR SALT THEREOF KANO SHINZO 1982-07-19 JP disclosed
JP-S56127365-A PREPARATION OF 5-CHLORO-2-BENZOTHIAZOLINONE DERIVATIVE TEIKOKU CHEM IND CORP LTD 1981-10-06 JP disclosed
JP-S5620581-A PREPARATION OF 5-CHLORO-3- 4- 2-HYDROXYETHYL -1-PIPERAZINYL - CARBONYLMETHYL-2-BENZOTHIAZOLINONE OR ITS SALT HAMARI YAKUHIN KOGYO KK 1981-02-26 JP disclosed
JP-S5620582-A NOVEL 2-BENZOTHIAZOLINONE DERIVATIVE AND ITS PREPARATION HAMARI YAKUHIN KOGYO KK 1981-02-26 JP disclosed