Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079806 | 1.00 | HRH4 (0.38) | HRH4HRH3IDH1 | |
| Hydrochloric Acid SCHEMBL1253917 | 0.99 | HRH4 (0.37) | HRH4HRH3IDH1 | |
| Hydrochloric Acid SCHEMBL1253916 | 0.99 | HRH4 (0.37) | HRH4HRH3IDH1 | |
| SCHEMBL5079057 | 0.90 | — | — | |
| SCHEMBL5079061 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL1253265 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL1253925 | 0.89 | — | — | |
| SCHEMBL5079049 | 0.83 | — | — | |
| SCHEMBL5079052 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL1251820 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575951-B1 | HETEROCYCLIC COMPOUNDS, METHODS OF MAKING THEM AND THEIR USE IN THERAPY | DEBIOPHARM INT SA (CH) | 2014-06-25 | — | — | EP | claimed |
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |