⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085976 | 0.88 | HPRT1 (0.32) | — | |
| SCHEMBL5080082 | 0.87 | CCNB2 (0.31) | — | |
| SCHEMBL5083016 | 0.87 | CDK5 (0.33) | — | |
| SCHEMBL5086060 | 0.86 | SERPINA3 (0.32) | — | |
| SCHEMBL5085999 | 0.80 | CDK1 (0.33) | — | |
| SCHEMBL5082996 | 0.80 | CDK1 (0.35) | — | |
| SCHEMBL5083003 | 0.76 | CCNE2 (0.31) | — | |
| SCHEMBL5086113 | 0.76 | HPRT1 (0.35) | — | |
| SCHEMBL5080057 | 0.76 | CCNE1 (0.36) | — | |
| SCHEMBL5082371 | 0.76 | CDK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |
| US-20060122391-A1 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |