Sugi Predict

Sugi Predict / Compounds / SCHEMBL5080887

SCHEMBL5080887

SCHEMBL5080887

CCOCC1(CO[Si](C)(C)c2ccc(C)cc2)c2ccccc2-c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 5/20 0.32
▸ HSD11B1 P28845 1/20 0.31
▸ ENPP3 O14638 1/20 0.30
▸ ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081766 0.92 PDK2 (0.36) PDK2
SCHEMBL5082359 0.91 SMN1; SMN2 (0.34) —
SCHEMBL5082280 0.90 PDK2 (0.33) PDK2
SCHEMBL5085336 0.86 PDK2 (0.33) PDK2
SCHEMBL5078695 0.82 SMN1; SMN2 (0.34) PDK2HSD11B1
SCHEMBL5080888 0.82 APP (0.31) —
SCHEMBL5078718 0.81 APEX1 (0.39) —
SCHEMBL5940616 0.81 PDK2 (0.41) PDK2
SCHEMBL5081819 0.80 CYP2C9 (0.33) PDK2
SCHEMBL29757337 0.80 APEX1 (0.40) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 — — US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 — — US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 — — US disclosed