SCHEMBL5081013

SCHEMBL5081013

CC(C)(O)CON1C(C)(C)CC(OC(=O)C(CC(=O)O)C2CC(C)(C)N(OCC(C)(C)O)C(C)(C)C2)CC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5083729 0.89 TSHR (0.31) TSHRKMT2A
SCHEMBL454638 0.87
SCHEMBL7717981 0.87
SCHEMBL454162 0.85
SCHEMBL27558288 0.77 CYP1A2 (0.32)
SCHEMBL12227670 0.77 TSHR (0.47) TSHRKMT2A
SCHEMBL5646805 0.77 KMT2A (0.34) TSHRKMT2A
SCHEMBL39577 0.76 KMT2A (0.35) TSHRKMT2A
SCHEMBL12020715 0.76 TSHR (0.35) TSHRKMT2A
SCHEMBL13958206 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517926-B1 OXYGEN TAILORING OF POLYETHYLENE FILM RESINS EXXONMOBIL CHEM PATENTS INC (US) 2008-07-23 EP disclosed
US-7285617-B2 Oxygen tailoring of polyethylene blow molding resins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-20060079664-A1 Oxygen tailoring of polyethylene blow molding resins EXXONMOBIL CHEMICAL PATENTS, INC. 2006-04-13 US disclosed
US-6989423-B2 Extrusion of polyolefins by conveying in melt mixing zones in the presence of oxygen and antioxidants for use as sheets having uniform thickness, elasticity and tensile strength EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2006-01-24 US disclosed
US-20040039131-A1 Oxygen tailoring of polyethylene film resins EXXONMOBIL CHEMICAL PATENTS INC. 2004-02-26 US disclosed