⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374989 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL4654297 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL2035817 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL57057 | 0.73 | — | — | |
| SCHEMBL4620039 | 0.70 | — | — | |
| SCHEMBL2810515 | 0.70 | — | — | |
| SCHEMBL614415 | 0.69 | — | — | |
| SCHEMBL8083586 | 0.69 | — | — | |
| SCHEMBL3934219 | 0.69 | — | — | |
| SCHEMBL82074 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386794-B1 | METHOD FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF STEROID SIDE CHAINS IN OPTICALLY ACTIVE FORM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-01-27 | — | — | EP | claimed |
| US-5089647-A | Method for preparing intermediates for the synthesis of steroid side chains in optically active form | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-02-18 | — | — | US | claimed |
| WO-1990010618-A1 | METHOD FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF STEROID SIDE CHAINS IN OPTICALLY ACTIVE FORM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-09-20 | — | — | WO | claimed |
| EP-0386794-A1 | Method for preparing intermediates for the synthesis of steroid side chains in optically active form | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-09-12 | — | — | EP | claimed |
| US-20080319042-A1 | Compositions and methods for treatment of liver disease | CALECO PHARMA CORP. | 2008-12-25 | — | — | US | disclosed |