SCHEMBL5081333

SCHEMBL5081333

C=C(C(=O)Oc1ccccc1)C(C)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.47
ATM Q13315 3/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
XBP1 P17861 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 2/20 0.42
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
NPY5R Q15761 1/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080216 0.87 ELANE (0.49) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL10006804 0.84 GAA (0.50) ELANEATMLMNATDP1HPGD
SCHEMBL28962125 0.82 HPGD (0.43) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL597721 0.81 ELANE (0.44) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL9574928 0.80 ELANE (0.46) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL13817458 0.80 HPGD (0.58) ELANEATMLMNAL3MBTL1TDP1
SCHEMBL27633065 0.80 KMT2A (0.43) ELANEATMLMNAMAPTL3MBTL1
Isobutane SCHEMBL28176404 0.79 ELANE (0.67) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL9745967 0.79 ELANE (0.45) ELANEATMLMNAMAPTL3MBTL1
SCHEMBL9746928 0.79 ELANE (0.45) ELANEATMLMNAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1144542-B1 POLYMER CEMENT ADDITIVE, CEMENT COMPOSITION AND PROCESS THEREWITH CONOCOPHILLIPS CO (US) 2006-07-19 EP claimed
EP-1144542-A4 CEMENT COMPOSITION AND PROCESS THEREWITH CONOCOPHILLIPS CO (US) 2004-06-09 EP claimed
EP-1144542-A1 CEMENT COMPOSITION AND PROCESS THEREWITH Phillips Petroleum Company (US) 2001-10-17 EP claimed
US-6124383-A CEMENT AND POLYMER ADJUVANT WHICH REDUCES WATER LOSS FROM CEMENT SLURRIES COMPRISING A TETRAPOLYMER OF AN UNSATURATED AMIDE, HYDROXY ACRYLATE, AND TWO MORE SPECIFIED MONOMERS SUCH AS VINYL MORPHOLINE AND A SECOND DIFFERENT UNSATURATED AMIDE PHILLIPS PETROLEUM COMPANY (US) 2000-09-26 US claimed
WO-2000039244-A1 CEMENT COMPOSITION AND PROCESS THEREWITH PHILLIPS PETROLEUM COMPANY (US) 2000-07-06 WO claimed
CN-100554290-C Few foreign, be difficult to gelation contain lactonic ring polymkeric substance and uses thereof NIPPON CATALYTIC CHEM IND (JP) 2009-10-28 CN disclosed
EP-1752475-B1 Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications NIPPON CATALYTIC CHEM IND (JP) 2008-11-05 EP disclosed
US-20070037962-A1 Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications NIPPON SHOKUBAI CO., LTD. (JP) 2007-02-15 US disclosed
EP-1752475-A1 Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications NIPPON SHOKUBAI CO., LTD. (JP) 2007-02-14 EP disclosed
CN-1911972-A Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications NIPPON CATALYTIC CHEM IND (JP) 2007-02-14 CN disclosed
EP-1144542-B1 POLYMER CEMENT ADDITIVE, CEMENT COMPOSITION AND PROCESS THEREWITH CONOCOPHILLIPS CO (US) 2006-07-19 EP disclosed
EP-1144542-A4 CEMENT COMPOSITION AND PROCESS THEREWITH CONOCOPHILLIPS CO (US) 2004-06-09 EP disclosed
EP-1144542-A1 CEMENT COMPOSITION AND PROCESS THEREWITH Phillips Petroleum Company (US) 2001-10-17 EP disclosed
US-6124383-A CEMENT AND POLYMER ADJUVANT WHICH REDUCES WATER LOSS FROM CEMENT SLURRIES COMPRISING A TETRAPOLYMER OF AN UNSATURATED AMIDE, HYDROXY ACRYLATE, AND TWO MORE SPECIFIED MONOMERS SUCH AS VINYL MORPHOLINE AND A SECOND DIFFERENT UNSATURATED AMIDE PHILLIPS PETROLEUM COMPANY (US) 2000-09-26 US disclosed
WO-2000039244-A1 CEMENT COMPOSITION AND PROCESS THEREWITH PHILLIPS PETROLEUM COMPANY (US) 2000-07-06 WO disclosed