Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466467 | 0.85 | TP53 (0.35) | TSHRTP53MEN1KMT2A | |
| SCHEMBL6109384 | 0.82 | TSHR (0.43) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL27845824 | 0.81 | TP53 (0.32) | TSHRTP53 | |
| SCHEMBL23045260 | 0.79 | TSHR (0.37) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL9746775 | 0.78 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL10705663 | 0.78 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL9746821 | 0.78 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL9747131 | 0.78 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL28667376 | 0.77 | — | — | |
| SCHEMBL3859257 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100554290-C | Few foreign, be difficult to gelation contain lactonic ring polymkeric substance and uses thereof | NIPPON CATALYTIC CHEM IND (JP) | 2009-10-28 | — | — | CN | disclosed |
| EP-1752475-B1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON CATALYTIC CHEM IND (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20070037962-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1752475-A1 | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-02-14 | — | — | EP | disclosed |
| CN-1911972-A | Lactone ring-containing polymer having few foreign matters and not easily causing gelation, and its applications | NIPPON CATALYTIC CHEM IND (JP) | 2007-02-14 | — | — | CN | disclosed |