Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | GSR | P00390 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL30531658 | 1.00 | KMT2A (0.79) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL508160 | 1.00 | KMT2A (0.79) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL23859817 | 0.96 | KMT2A (0.73) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL5964542 | 0.94 | KMT2A (0.83) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL10888199 | 0.91 | KMT2A (0.86) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL10888184 | 0.91 | KMT2A (0.86) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL27536616 | 0.90 | KMT2A (0.76) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL104313 | 0.89 | KMT2A (0.83) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL6555864 | 0.89 | KMT2A (0.83) | KMT2APMP22ALOX15BLMGSR | |
| Glutamine SCHEMBL3059857 | 0.89 | KMT2A (0.83) | KMT2APMP22ALOX15BLMGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250064766-A1 | COMPOSITIONS AND METHODS FOR INCREASING ARGININE AND NITRIC OXIDE LEVELS | VIREO SYSTEMS, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| WO-2025043178-A1 | COMPOSITIONS AND METHODS FOR INCREASING ARGININE AND NITRIC OXIDE LEVELS | VIREO SYSTEMS, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-116437823-A | Extruded food composition comprising cultured animal cells and method of making same | 优良肉品公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4203705-A1 | EXTRUDATE FOOD COMPOSITIONS COMPRISING CULTIVATED ANIMAL CELLS AND METHODS OF PRODUCTION THEREOF | Good Meat, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-115397972-A | In vitro poultry food | 优良肉品公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022132983-A1 | FOOD PRODUCTS COMPRISING CULTIVATED BOVINE CELLS AND METHODS THEREOF | GOOD MEAT, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20220183316-A1 | FOOD PRODUCTS COMPRISING CULTIVATED BOVINE CELLS AND METHODS THEREOF | AHIMSA FOUNDATION, AS COLLATERAL AGENT | 2022-06-16 | — | — | US | disclosed |
| EP-3983529-A1 | IN VITRO AVIAN FOOD PRODUCT | Good Meat, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |
| WO-2022047263-A1 | EXTRUDATE FOOD COMPOSITIONS COMPRISING CULTIVATED ANIMAL CELLS AND METHODS OF PRODUCTION THEREOF | GOOD MEAT, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| US-20200392461-A1 | IN VITRO AVIAN FOOD PRODUCT | AHIMSA FOUNDATION | 2020-12-17 | — | — | US | disclosed |
| US-20120219531-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-08-30 | — | — | US | disclosed |
| EP-2479260-A1 | Microcarriers for stem cell culture | Agency For Science, Technology And Research (SG) | 2012-07-25 | — | — | EP | disclosed |
| US-20120028352-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-02-02 | — | — | US | disclosed |
| US-20110143433-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-16 | — | — | US | disclosed |
| US-20110129919-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-02 | — | — | US | disclosed |
| US-20110111498-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-05-12 | — | — | US | disclosed |
| US-20110014693-A1 | Microcarriers For Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-01-20 | — | — | US | disclosed |
| EP-2271747-A2 | MICROCARRIERS FOR STEM CELL CULTURE | Agency for Science, Technology And Research (SG) | 2011-01-12 | — | — | EP | disclosed |
| US-20100093053-A1 | Microcarriers for Stem Cell Culture | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-04-15 | — | — | US | disclosed |
| WO-2009116951-A2 | MICROCARRIERS FOR STEM CELL CULTURE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219531-A1 | Microcarriers for Stem Cell Culture | KIT, BST2, CXCL12 | KMT2A 1123/4885PMP22 1619/4885ALOX15 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.