Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093251 | 0.82 | CYP3A4 (0.40) | MAPTCYP3A4HDAC1HDAC3HDAC4 | |
| SCHEMBL726647 | 0.82 | CYP3A4 (0.40) | MAPTCYP3A4HDAC1HDAC3HDAC4 | |
| SCHEMBL726717 | 0.66 | MAPT (0.49) | MAPTCASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL726718 | 0.66 | MAPT (0.49) | MAPTCASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL726426 | 0.64 | MAPT (0.47) | MAPTCASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL726425 | 0.64 | MAPT (0.47) | MAPTCASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL1093253 | 0.64 | CYP3A4 (0.40) | MAPTCYP3A4HDAC1HDAC3HDAC4 | |
| SCHEMBL726646 | 0.64 | CYP3A4 (0.40) | MAPTCYP3A4HDAC1HDAC3HDAC4 | |
| SCHEMBL14303911 | 0.62 | MAPT (0.69) | MAPTCASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL726940 | 0.62 | MAPT (0.61) | MAPTCASP1CASP7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | disclosed |