SCHEMBL5082289

SCHEMBL5082289

CC(C)(C)[Si](C)(C)OCC1(CO[Si](C)(C)C(C)(C)C)c2ccccc2-c2ccc(F)cc21

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080883 0.87 APEX1 (0.35) PDK2
SCHEMBL5082215 0.86 PDK2 (0.44) PDK2
SCHEMBL5081756 0.83 PDK2 (0.34) PDK2
SCHEMBL5081787 0.83 PDK2 (0.41) PDK2
SCHEMBL5940614 0.82 PDK2 (0.40) PDK2
SCHEMBL5082322 0.81 PDK2 (0.42) PDK2
SCHEMBL5085385 0.81 PDK2 (0.40) PDK2
SCHEMBL5080936 0.80 PDK2 (0.32) PDK2
SCHEMBL5084662 0.80 PDK2 (0.39) PDK2
SCHEMBL4912255 0.79 PDK2 (0.55) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-6822109-B2 TRIHYDROCARBYLSILYLATION; ADDITION POLYMERIZATION OF OLEFINS CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2004-11-23 US claimed
US-20040106814-A1 Silicon ether compound, a method for the preparation thereof and use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2004-06-03 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed
US-6822109-B2 TRIHYDROCARBYLSILYLATION; ADDITION POLYMERIZATION OF OLEFINS CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2004-11-23 US disclosed
US-20040106814-A1 Silicon ether compound, a method for the preparation thereof and use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2004-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106814-A1 Silicon ether compound, a method for the preparation thereof and use thereof SIK1, CDK20, SGMS1 PDK2 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.