Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | CACNA2D1 | P54289 | 16/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3377 | 0.99 | SLC6A2 (0.61) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| Bromide SCHEMBL6476676 | 0.81 | SLC6A2 (0.40) | SLC6A2SLC6A4CACNA2D1 | |
| Oxalic Acid SCHEMBL3731 | 0.74 | SLC6A4 (0.88) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL20292585 | 0.74 | CACNA2D1 (1.00) | SLC6A2SLC6A4CACNA2D1 | |
| SCHEMBL20292575 | 0.74 | CACNA2D1 (0.84) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL23521668 | 0.72 | SLC6A2 (0.70) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL21742710 | 0.72 | SLC6A2 (0.70) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL30788076 | 0.72 | SLC6A2 (0.70) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL20292539 | 0.71 | CACNA2D1 (1.00) | SLC6A2SLC6A4CACNA2D1SLC6A3 | |
| SCHEMBL20292508 | 0.71 | CACNA2D1 (1.00) | SLC6A2SLC6A4CACNA2D1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |
| CN-1099284-C | Treatment of incontinence | LILLY CO ELI (US) | 2003-01-22 | — | — | CN | disclosed |