Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 9/20 | 0.59 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413290 | 1.00 | TP53 (0.60) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL19994224 | 0.95 | TP53 (0.53) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9473890 | 0.88 | NR1H4 (0.60) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL6856721 | 0.87 | TP53 (0.59) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL31087875 | 0.87 | TP53 (0.59) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL10338193 | 0.87 | TP53 (0.59) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL6856724 | 0.87 | TP53 (0.59) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL10338195 | 0.87 | TP53 (0.59) | TP53TSHRPLA2G4BRARBNR5A1 | |
| SCHEMBL3689744 | 0.85 | TP53 (0.48) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1333051 | 0.84 | NR1H4 (0.62) | TP53TSHRPLA2G4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408077-B2 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20040162431-A1 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORP. | 2004-08-19 | — | — | US | disclosed |
| EP-1373183-A1 | PERMANENT SURFACE MODIFIERS | Ciba SC Holding AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002072530-A1 | PERMANENT SURFACE MODIFIERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-09-19 | — | — | WO | disclosed |