Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.47 |
| ▸ | ADA | P00813 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551409 | 1.00 | ADORA2A (0.54) | ADORA2APRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL731577 | 0.83 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL19536253 | 0.83 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL19536251 | 0.83 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL5844191 | 0.83 | ADORA2A (0.58) | ADORA2APRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL4552286 | 0.81 | ADORA2A (0.50) | ADORA2APRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL4001514 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3ADORA1ADORA2BADA | |
| SCHEMBL6727038 | 0.79 | PRMT5 (0.46) | ADORA2APRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL6727224 | 0.79 | PRMT5 (0.46) | ADORA2APRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL16311924 | 0.79 | ADORA2A (0.56) | ADORA2APRMT5WDR77ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127613-A1 | NEW PHARMACEUTICAL COMPOSITIONS | SCYNEXIS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |