Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.80 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053289 | 1.00 | PPARG (0.80) | PPARGPPARASLC22A12SLC6A9ACP3 | |
| SCHEMBL4576498 | 0.93 | PPARG (0.82) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| Metaglidasen SCHEMBL14606136 | 0.89 | PPARG (1.00) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| Metaglidasen SCHEMBL29387584 | 0.89 | PPARG (1.00) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| Metaglidasen SCHEMBL2443233 | 0.89 | PPARG (1.00) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| Mbx-102 Acid Form SCHEMBL12189837 | 0.89 | PPARG (1.00) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| SCHEMBL18174876 | 0.89 | PPARG (0.76) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| SCHEMBL18174877 | 0.89 | PPARG (0.76) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| SCHEMBL18174878 | 0.89 | PPARG (0.76) | PPARGPPARASLC22A12SLC6A9KDM4E | |
| SCHEMBL4575950 | 0.88 | PPARG (0.67) | PPARGPPARASLC22A12SLC6A9ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937620-A2 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES | Metabolex Inc. (US) | 2008-07-02 | — | — | EP | claimed |
| WO-2007038277-A2 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES | METABOLEX, INC. (US) | 2007-04-05 | — | — | WO | claimed |