Toluene

Toluene

SCHEMBL5084004

C=C.C=CCCCC.Cc1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44
PCSK9 Q8NBP7 1/20 0.37
HTT P42858 1/20 0.34
ATM Q13315 1/20 0.33
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LTA4H P09960 1/20 0.33
PDE5A O76074 1/20 0.33
C5AR1 P21730 1/20 0.33
GPR52 Q9Y2T5 1/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL998833 0.98 TSHR (0.58) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL8147547 0.90 TSHR (0.61) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL11023406 0.90 TSHR (0.61) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL782975 0.90 TSHR (0.61) TSHRALDH1A1LMNAALOX12ACHE
Heptane SCHEMBL6130166 0.90 TSHR (0.61) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL11011055 0.90 TSHR (0.61) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL9153035 0.89 TSHR (0.55) TSHRALDH1A1LMNAALOX12ACHE
Toluene SCHEMBL20497325 0.84 TSHR (0.53) TSHRALDH1A1
Biphenyl SCHEMBL27462127 0.83 TSHR (0.61) TSHRALDH1A1HPGD
Toluene SCHEMBL20497322 0.83 TSHR (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987047-A2 PROCESS FOR GENERATING ALPHA OLEFIN COMONOMERS ExxonMobil Chemical Patents Inc. (US) 2008-11-05 EP disclosed
WO-2007092217-A2 PROCESS FOR GENERATING LINEAR ALPHA OLEFIN COMONOMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-08-16 WO disclosed
WO-2007092136-A2 PROCESS FOR GENERATING ALPHA OLEFIN COMONOMERS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2007-08-16 WO disclosed