Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077870 | 0.86 | MGAM (0.34) | L3MBTL1 | |
| SCHEMBL5690613 | 0.86 | MGAM (0.34) | L3MBTL1 | |
| SCHEMBL5080768 | 0.86 | MGAM (0.34) | L3MBTL1 | |
| SCHEMBL25230285 | 0.83 | TP53 (0.34) | MAPTL3MBTL1TP53 | |
| SCHEMBL17925703 | 0.81 | TP53 (0.33) | MAPTL3MBTL1TP53 | |
| SCHEMBL25230661 | 0.81 | TP53 (0.33) | MAPTL3MBTL1TP53 | |
| SCHEMBL5690582 | 0.81 | CYP1A2 (0.42) | — | |
| SCHEMBL5690578 | 0.81 | CYP1A2 (0.42) | — | |
| SCHEMBL5690588 | 0.81 | CYP1A2 (0.42) | — | |
| SCHEMBL6838803 | 0.80 | TSHR (0.34) | MAPTL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912936-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007010387-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-25 | — | — | WO | disclosed |