SCHEMBL5084723

SCHEMBL5084723

C=C(C)C(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378225 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL28886777 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL5084831 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL2140463 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL55494 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL650003 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL5086531 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL2396170 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL7894072 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL7532264 1.00 TSHR (0.36) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831305-B1 GRAFT COPOLYMERS WITH SEGMENTED ARMS COATINGS FOREIGN IP CO LLC (US) 2015-08-12 EP disclosed
US-7402624-B2 Graft copolymers with segmented arms and their preparation and use E.I. DU PONT DE NEMOURS & COMPANY (US) 2008-07-22 US disclosed
EP-1831305-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-12 EP disclosed
WO-2006052981-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-18 WO disclosed
US-20060100305-A1 Graft copolymers with segmented arms and their preparation and use AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-05-11 US disclosed