Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 3/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025400 | 1.00 | CCNE2 (0.42) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5036104 | 0.87 | MAP2K7 (0.48) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5036101 | 0.87 | MAP2K7 (0.48) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5022604 | 0.86 | ADORA2A (0.46) | NQO2ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5091471 | 0.86 | ADORA2A (0.46) | NQO2ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL5022748 | 0.86 | ACVR1 (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5521214 | 0.86 | ACVR1 (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5022740 | 0.86 | ACVR1 (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5521204 | 0.86 | ACVR1 (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL27597784 | 0.84 | MTOR (0.41) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474145-B1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | EP | claimed |