SCHEMBL508486

SCHEMBL508486

CCCCCCCc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 1.00
TSHR P16473 1/20 1.00
RARB P10826 5/20 0.54
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 2/20 0.54
MAPT P10636 2/20 0.54
KMT2A Q03164 2/20 0.54
RARA P10276 1/20 0.54
MTOR P42345 1/20 0.54
CYP19A1 P11511 3/20 0.52
CYP2A6 P11509 1/20 0.52
ESR1 P03372 2/20 0.52
ADRA2A P08913 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
TACR2 P21452 2/20 0.52
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
KDM4E B2RXH2 2/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8022050 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL1896035 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL1894341 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL25181545 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL1325933 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL25190474 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL20700 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL25187484 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL1890052 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1
SCHEMBL10456882 1.00 HSD17B10 (1.00) HSD17B10TSHRRARBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529340-B Self-positioning flexible circularly polarized light conversion film and preparation method thereof 中国科学技术大学 2026-05-12 CN claimed
US-12291651-B2 Liquid crystal-infused slippery anti-fouling surfaces WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-05-06 US claimed
US-20250122350-A1 CELLULOSE-ENABLED ORIENTATIONALLY ORDERED FLEXIBLE GELS UNIV COLORADO REGENTS (US) 2025-04-17 US claimed
WO-2025059295-A1 POLYMER INTERLAYERS PROVIDED WITH ELECTROCHROMIC MATERIALS SOLUTIA INC. (US) 2025-03-20 WO claimed
WO-2025059262-A1 POLYMER INTERLAYERS PROVIDED WITH ELECTROCHROMIC MATERIALS SOLUTIA INC. (US) 2025-03-20 WO claimed
WO-2025059252-A1 POLYMER INTERLAYERS PROVIDED WITH ELECTROCHROMIC MATERIALS SOLUTIA INC. (US) 2025-03-20 WO claimed
WO-2025059249-A1 POLYMER INTERLAYERS PROVIDED WITH ELECTROCHROMIC MATERIALS SOLUTIA INC. (US) 2025-03-20 WO claimed
CN-119529340-A Self-positioning flexible circularly polarized light conversion film and preparation method thereof 中国科学技术大学 2025-02-28 CN claimed
CN-118956301-A Electrolytic adhesive containing stable polymer and preparation method thereof 浙江中特化工有限公司 2024-11-15 CN claimed
WO-2024227162-A1 DROPLET IMPACT-INDUCED CHEMICAL RELEASE FROM STRUCTURED FLUIDS OHIO STATE INNOVATION FOUNDATION (US) 2024-10-31 WO claimed
US-4113647-A ELECTRO-OPTIC DISPLAY DEVICE THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1978-09-12 US claimed
US-4096086-A CONTAINING A P-CYANOPHENYL BENZOATE AND A PHENYL BENZOATE ETHER KABUSHIKI KAISHA SUWA SEIKOSHA (JA) 1978-06-20 US claimed
US-4083797-A ALKYLCYANO-BIPHENYL TYPE, ESTER AND CHLORO-SUBSTITUTED DIESTER TYPES BECKMAN INSTRUMENTS, INC. (US) 1978-04-11 US claimed
US-4076646-A O- OR M-TERPHENYLS HITACHI, LTD. (JA) 1978-02-28 US claimed
US-4069167-A 4-CYANO-4\"-N-ALKYLBI- AND TERPHENYLS, 4-CYANO-4\"-N-ALKOXYBIPHENYLS CHISSO CORPORATION (JA) 1978-01-17 US claimed
US-4066570-A OPTICAL CELLS, NEMATIC MIXTURES, LIQUID CRYSTALS HOFFMAN-LA ROCHE INC. (US) 1978-01-03 US claimed
US-4061587-A Liquid crystalline cinnamic acid esters HOFFMANN-LA ROCHE INC. (US) 1977-12-06 US claimed
US-4053431-A DIELECTRICS IN ELECTRO-OPTICAL DEVICES HOFFMANN-LA ROCHE INC. (US) 1977-10-11 US claimed
US-4043935-A Liquid crystal composition having high dielectric anisotropy and display device incorporating same KABUSHIKI KAISHA SUWA SEIKOSHA (JA) 1977-08-23 US claimed
US-3954653-A P-SUBSTITUTED-P-CYANOAZOXYBENZENE KABUSHIKI KAISHA SUWA SEIKOSHA (JA) 1976-05-04 US claimed