SCHEMBL5084877

SCHEMBL5084877

CSC1CCCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23114589 1.00
SCHEMBL14530526 0.84
SCHEMBL22759816 0.84
SCHEMBL1145410 0.84
SCHEMBL9035475 0.75
SCHEMBL19121220 0.75
SCHEMBL9036008 0.75
SCHEMBL9036016 0.75
SCHEMBL22879260 0.72
SCHEMBL9035649 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303502-A1 HETEROARYL AND HETEROCYCLYL COMPOUNDS SIGILON THERAPEUTICS, INC. 2023-09-28 US disclosed
WO-2022082180-A1 COMBINATIONS OF BCL-2 INHIBITORS WITH CHEMOTHERAPEUTIC AGENTS RECURIUM IP HOLDINGS, LLC (US) 2022-04-21 WO disclosed
US-20220119386-A1 FUSED RING DERIVATIVE USED AS FGFR4 INHIBITOR JACOBIO PHARMACEUTICALS CO LTD (CN) 2022-04-21 US disclosed
US-11174245-B2 Benzimidazole compounds and derivatives as EGFR inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-11-16 US disclosed
EP-2912082-B1 POLYUREA THAT IS PARTICULARLY USEFUL AS AN ADHESION PRIMER FOR ADHERING METAL TO RUBBER MICHELIN & CIE (FR) 2021-08-04 EP disclosed
US-20200377476-A1 NEW BENZIMIDAZOLE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2020-12-03 US disclosed
US-9845376-B2 Polyurea that is particularly useful as an adhesion primer for adhering metal to rubber COMPAGNIE GENERALE DES ESTABLISSEMENTS MICHELIN (FR) 2017-12-19 US disclosed
US-9845376-B2 Polyurea that is particularly useful as an adhesion primer for adhering metal to rubber COMPAGNIE GENERALE DES ESTABLISSEMENTS MICHELIN (FR) 2017-12-19 US disclosed
US-9617372-B2 Sulphur-comprising polyaromatic polyamine that can be used in the synthesis of polyurea COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-04-11 US disclosed
US-9617372-B2 Sulphur-comprising polyaromatic polyamine that can be used in the synthesis of polyurea COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-04-11 US disclosed
WO-2001051527-A1 PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051526-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
EP-0450066-B1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMA CO LTD (JP) 1996-09-11 EP disclosed
US-5401740-A FOR INHIBITING PLATELET AGGREGATION OTSUKA PHARMACEUTICAL CO. (JP) 1995-03-28 US disclosed
US-5227381-A Anticoagulant OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-13 US disclosed
EP-0450066-A1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-10-09 EP disclosed