Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5084899

CSCC[C@H](NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 15/20 0.90
FNTB P49356 15/20 0.90
PGGT1B P53609 7/20 0.90
TDP1 Q9NUW8 2/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5084894 1.00 FNTA (0.90) FNTAFNTBPGGT1BTDP1
Trifluoroacetic Acid SCHEMBL29394662 1.00 FNTA (0.90) FNTAFNTBPGGT1BTDP1
SCHEMBL2722114 0.95 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL4148121 0.95 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL16111993 0.95 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL8492288 0.95 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL17534949 0.95 FNTA (1.00) FNTAFNTBPGGT1BTDP1
Trifluoroacetic Acid SCHEMBL5078478 0.93 FNTA (0.90) FNTAFNTBPGGT1BTDP1
Trifluoroacetic Acid SCHEMBL5078474 0.93 FNTA (0.90) FNTAFNTBPGGT1BTDP1
Trifluoroacetic Acid SCHEMBL29395402 0.93 FNTA (0.90) FNTAFNTBPGGT1BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106667988-A Application of farnesyltransferase inhibitors in preparation of medicine for facilitated cholinergic nerve system 南京医科大学 2017-05-17 CN disclosed
US-20080139457-A1 Therapeutic compositions comprising chorionic gonadotropins and HMG CoA reductase inhibitors VIRGINIA COMMONWEALTH UNIVERSITY (US) 2008-06-12 US disclosed
WO-2007035395-A9 THERAPEUTIC COMPOSITIONS COMPRISING CHORIONIC GONADOTROPINS AND HMG COA REDUCTASE INHIBITORS UNIV VIRGINIA COMMONWEALTH (US) 2007-06-14 WO disclosed
WO-2007035395-A2 THERAPEUTIC COMPOSITIONS COMPRISING CHORIONIC GONADOTROPINS AND HMG COA REDUCTASE INHIBITORS VIRGINIA COMMONWEALTH UNIVERSITY INTELLECTUAL PROPERTY FOUNDATION (US) 2007-03-29 WO disclosed