Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 11/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11519518 | 0.97 | TSHR (0.41) | TSHRTHRBFDPSGGPS1DNM1 | |
| SCHEMBL414589 | 0.97 | TSHR (0.41) | TSHRTHRBFDPSGGPS1CES2 | |
| Bromide SCHEMBL5088494 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1DNM1 | |
| Bromide SCHEMBL583910 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1DNM1 | |
| SCHEMBL5474322 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1CES2 | |
| SCHEMBL5473271 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1CES2 | |
| Iodide SCHEMBL5089252 | 0.94 | TSHR (0.39) | TSHRTHRBFDPSGGPS1CES2 | |
| Bromide SCHEMBL1250790 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1DNM1 | |
| SCHEMBL17529793 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1CES2 | |
| SCHEMBL10408402 | 0.94 | TSHR (0.47) | TSHRTHRBFDPSGGPS1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119144153-A | Flame-retardant antistatic polyamide and preparation method thereof | 中化学科学技术研究有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-115920970-B | Heterobinuclear copper-based catalyst for synthesizing chloroethylene and preparation method and application thereof | 浙江工业大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118026611-A | Ash-based anti-crack road concrete and preparation method thereof | 宁夏亿丰砼业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-115678140-B | Antistatic ultra-high molecular weight polyethylene based on ionic liquid and preparation method thereof | 广州市香港科大霍英东研究院 | 2024-04-26 | — | — | CN | claimed |
| CN-117887062-A | Method for controllably synthesizing low molecular weight narrow distribution polyether polyol | 中国科学院过程工程研究所 | 2024-04-16 | — | — | CN | claimed |
| CN-117887059-A | Method for selectively synthesizing polycarbonate or cyclic carbonate | 中国科学院过程工程研究所 | 2024-04-16 | — | — | CN | claimed |
| US-20230295360-A1 | METHOD FOR PREPARING POLYION THIN FILM, AND POLYION THIN FILM AND DETECTION KIT | ANKON MEDICAL TECHNOLOGIES (SHANGHAI) CO., LTD. (CN) | 2023-09-21 | — | — | US | claimed |
| CN-116574226-B | Bio-based acidic color fixing agent and preparation method and application thereof | 珠海华大浩宏新材料有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116574226-A | Bio-based acidic color fixing agent and preparation method and application thereof | 珠海华大浩宏新材料有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116284122-A | Ultraviolet light curing flame-retardant monomer and preparation method and application thereof | 深圳市宝安区新材料研究院 | 2023-06-23 | — | — | CN | claimed |
| CN-110743556-B | Copper-based alloy catalyst and preparation method and application thereof | 浙江工业大学 | 2020-08-21 | — | — | CN | claimed |
| CN-111435705-A | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2020-07-21 | — | — | CN | claimed |
| CN-107803222-B | Ruthenium complex catalyst for acetylene hydrochlorination | 浙江工业大学 | 2020-06-09 | — | — | CN | claimed |
| CN-111250158-A | Carbon-supported alkaline ionic liquid-metal catalyst and preparation and application thereof | 浙江工业大学 | 2020-06-09 | — | — | CN | claimed |
| CN-111151299-A | Copper alkoxide complex catalyst, preparation method thereof and application thereof in acetylene hydrochlorination | 浙江工业大学 | 2020-05-15 | — | — | CN | claimed |
| CN-110813380-A | Copper ketone complex catalyst, preparation method thereof and application thereof in acetylene hydrochlorination | 浙江工业大学 | 2020-02-21 | — | — | CN | claimed |
| CN-110828881-A | Dual-ion battery and preparation method thereof | 深圳先进技术研究院 | 2020-02-21 | — | — | CN | claimed |
| CN-110743624-A | Acetylene hydrochlorination copper-based catalyst and preparation method and application thereof | 浙江工业大学 | 2020-02-04 | — | — | CN | claimed |
| CN-110743556-A | Copper-based alloy catalyst and preparation method and application thereof | 浙江工业大学 | 2020-02-04 | — | — | CN | claimed |
| CN-110743621-A | Trivalent copper catalyst, preparation method thereof and application thereof in acetylene hydrochlorination | 浙江工业大学 | 2020-02-04 | — | — | CN | claimed |