Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 8/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | GUSB | P08236 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857122 | 0.86 | PTPN5 (0.73) | ARMAOBMAOACHRNA7BCHE | |
| SCHEMBL10829866 | 0.86 | PTPN5 (0.73) | ARMAOBMAOACHRNA7BCHE | |
| SCHEMBL8106959 | 0.82 | BCHE (0.75) | ARMAOBMAOACHRNA7BCHE | |
| SCHEMBL8106958 | 0.82 | BCHE (0.75) | ARMAOBMAOACHRNA7BCHE | |
| SCHEMBL13857110 | 0.78 | AR (1.00) | ARMAOBCHRNA7BCHEGUSB | |
| SCHEMBL15620265 | 0.77 | MAOB (0.73) | ARMAOBMAOAMAPT | |
| SCHEMBL15620266 | 0.77 | MAOB (0.73) | ARMAOBMAOAMAPT | |
| SCHEMBL28723350 | 0.77 | CXCL12 (0.59) | MAOBCHRNA7MAPT | |
| SCHEMBL25190630 | 0.76 | MAOB (1.00) | ARMAOBMAOABCHEGUSB | |
| SCHEMBL5138128 | 0.76 | MAOB (1.00) | ARMAOBMAOABCHEGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |