Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568111 | 0.76 | CNR2 (0.50) | CNR2CNR1IDO1NUDT1P2RX7 | |
| SCHEMBL14567764 | 0.75 | CNR2 (0.49) | CNR2CNR1IDO1CYP2A6CYP2B6 | |
| SCHEMBL5084514 | 0.74 | CNR2 (0.57) | CNR2CNR1IDO1NUDT1P2RX7 | |
| SCHEMBL5085230 | 0.74 | CNR2 (0.48) | CNR2CNR1IDO1NUDT1P2RX7 | |
| SCHEMBL14051355 | 0.72 | CNR2 (0.52) | CNR2CNR1IDO1P2RX7CYP2D6 | |
| SCHEMBL5085295 | 0.71 | CNR2 (0.54) | CNR2CNR1IDO1NUDT1P2RX7 | |
| SCHEMBL5087450 | 0.71 | CNR2 (0.54) | CNR2CNR1IDO1NUDT1P2RX7 | |
| SCHEMBL14051391 | 0.70 | CNR2 (0.49) | CNR2CNR1IDO1 | |
| SCHEMBL1764977 | 0.69 | HTR2C (0.47) | CNR2CNR1IDO1NUDT1MAPK1 | |
| SCHEMBL14051353 | 0.69 | CNR2 (0.52) | CNR2CNR1IDO1NUDT1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| WO-2007022938-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007022938-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |