SCHEMBL5085449

SCHEMBL5085449

CN1C=CC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7856091 0.97
SCHEMBL13720851 0.71
SCHEMBL28922238 0.63
SCHEMBL17797280 0.63
SCHEMBL13057839 0.63
SCHEMBL4165206 0.62
SCHEMBL1319763 0.62
SCHEMBL506619 0.62
SCHEMBL8807426 0.62
SCHEMBL11732960 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112125889-A Preparation method of 7-bromo-2- (1-methyl-1H-pyrazol-4-yl) quinoxaline 苏州明锐医药科技有限公司 2020-12-25 CN claimed
US-20260055121-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LTD (GB) 2026-02-26 US disclosed
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NodThera Limited (GB) 2025-07-10 US disclosed
US-12263171-B2 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use MERCK SHARP & DOHME LLC (US) 2025-04-01 US disclosed
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NodThera Limited (GB) 2025-03-11 US disclosed
US-20250009917-A1 MACROCYCLE CONTAINING COMPOUNDS AND RADIOLABELLED COMPLEXES THEREOF, AS LIGANDS IN TARGETED RADIOTHERAPY APPLICATIONS THE UNIVERSITY OF MELBOURNE (AU) 2025-01-09 US disclosed
US-20250011291-A1 KEAP1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2025-01-09 US disclosed
EP-4408839-A1 MACROCYCLE CONTAINING COMPOUNDS AND RADIOLABELLED COMPLEXES THEREOF, AS LIGANDS IN TARGETED RADIOTHERAPY APPLICATIONS The University of Melbourne (AU) 2024-08-07 EP disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
CN-118317957-A Macrocyclic-containing compounds and radiolabeled complexes thereof as ligands in targeted radiotherapy applications 墨尔本大学 2024-07-09 CN disclosed
US-5965566-A A WATER SOLUBLE BIOLOGICAL ACTIVE DRUG CONJUGATED WITH POLYOXYETHYLENE GLYCOL THROUGH A HYDROLYZABLE ESTER LINKAGING SPACER; CONTROLLED RELEASE PROPERTIES ENZON, INC. (US) 1999-10-12 US disclosed
US-5948860-A OLEFIN TYPE ELASTOMER; AND A POLAR GROUP-CONTAINING OLEFIN POLYMER COMPOSITION OBTAINED BY HEATING AN OLEFIN POLYMER CONTAINING A CARBOXYL GROUP OR AN ACID ANHYDRIDE GROUP IN ITS MOLECULE AND AN AMINO COMPOUND. MITSUI CHEMICALS, INC. (JP) 1999-09-07 US disclosed
US-5840900-A POLYETHERS, POLYAMIDE POLYMERS WITH PRODRUGS ENZON, INC. (US) 1998-11-24 US disclosed
EP-0612800-B1 Propylene polymer compositions MITSUI PETROCHEMICAL IND (JP) 1997-10-29 EP disclosed
CN-1163645-A Paper products containing vegetable oil based chemical softening composition PROCTER & GAMBLE (US) 1997-10-29 CN disclosed
EP-0782646-A1 PAPER PRODUCTS CONTAINING A VEGETABLE OIL BASED CHEMICAL SOFTENING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1997-07-09 EP disclosed
US-5587476-A REACTION PRODUCT OF A DIAMINE WITH A FULLERENE; ELECTROCONDUCTIVE HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-24 US disclosed
US-5510000-A Paper products containing a vegetable oil based chemical softening composition THE PROCTER & GAMBLE COMPANY (US) 1996-04-23 US disclosed
WO-1996009437-A1 PAPER PRODUCTS CONTAINING A VEGETABLE OIL BASED CHEMICAL SOFTENING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1996-03-28 WO disclosed
EP-0612800-A1 Propylene polymer compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-08-31 EP disclosed