Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786440 | 0.99 | CYP2D6 (0.49) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL4837236 | 0.97 | CYP2D6 (0.47) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1785791 | 0.90 | CYP1A2 (0.54) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1785115 | 0.83 | CYP2D6 (0.45) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL4839038 | 0.82 | CYP2D6 (0.46) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1784682 | 0.82 | CYP2D6 (0.49) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1784161 | 0.82 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1783575 | 0.80 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1785516 | 0.78 | CYP2D6 (0.43) | CYP2D6CYP1A2CYP2C19LMNATSHR | |
| SCHEMBL1784827 | 0.78 | CYP2D6 (0.55) | CYP2D6CYP1A2CYP2C19LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332455-B2 | Catalyst component and catalyst for olefin polymerization as well as use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-02-19 | — | — | US | disclosed |
| US-20050119427-A1 | Catalyst component and catalyst for olefin polymerization as well as use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-06-02 | — | — | US | disclosed |