Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.44 |
| ▸ | IL1RN | P18510 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661213 | 0.80 | TSHR (0.51) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4989663 | 0.78 | TSHR (0.49) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL27542815 | 0.78 | TSHR (0.49) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4558954 | 0.77 | KMT2A (0.47) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL17403338 | 0.76 | TSHR (0.64) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL8761 | 0.76 | TSHR (0.64) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL28570306 | 0.76 | ACE (0.56) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4984701 | 0.74 | TSHR (0.49) | TSHRKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16201815 | 0.73 | ERAP1 (0.46) | TSHRKMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL5607432 | 0.73 | CYP2C19 (0.46) | SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508348-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | claimed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | claimed |