Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 20/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5086349 | 0.98 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL5302700 | 0.94 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5090502 | 0.91 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17029602 | 0.90 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17029614 | 0.87 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7900796 | 0.85 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3518106 | 0.84 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3465903 | 0.84 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3465901 | 0.84 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7899271 | 0.84 | SLC6A4 (0.72) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |